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Herculin MRF-4 is really something all together different and truly the first of its kind. Created by Dr. Jose Antonio and Dr. Darryn Willoughby, it’s the world’s 1st Pre-Workout Muscle Generator. What does that mean? It means that until now, sport supplements focused on the concept of repairing the damage done to muscles during workouts. Though somewhat effective, at best post-workout recovery is still a very limited and reactive approach to building muscle mass and dramatically increasing strength and power.
What Herculin MRF-4 is able to do is utilize your body’s own biological make-up and timing mechanisms so your body works efficiently before, during and after workouts. To do so, Drs Antonio and Willoughby first identified the 8 known pathways with which the human body is able to build muscle (anabolic activity).
1. Nutrient Timing
2. Protein Synthesis
3. Protein Degredation
4. Myogenic Regulatory Factor
5. Satellite Cell Activity
6. Energy Restoration
7. Muscle Membrane Support
8. Immune Support
The most important and anabolic of those pathways, being MRF-4. Herculin MRF-4 has been scientifically created to both effectively stimulate MRF-4, as well as effectively activate the other 7 primary anabolic pathways; giving you the ability to pack on more muscle than ever before, using just one simple pre-workout drink taken 30 minutes before training. There’s no loading or off-day maintenance. There’s no measuring or empty promises. Instead, Herculin MRF-4 will forever change your supplement regimen! Its already achieved something not seen since the inception of creatine into the mainstream market…the creation of a whole new category of supplements-Pre-Workout Muscle Generator.
The technology in Herculin MRF-4 has been awarded two U.S. Patents, which means no other company can duplicate it!
U.S. Patent
#5,925,378
U.S. Patent # 6,294,579
Patents Pending (International and
Domestic)
Drs. Antonio and Willoughby took the technology provided by these patented delivery systems and combined them with years of the most current research on muscle growth. Much of which [research in the area of myogenic growth factors], being pioneered by Dr Willoughby. This allowed for a breakthrough formula which combines the art of micro-nutrient delivery with proven scientific data.
The Nucleation, or base concept, of Herculin MRF-4 is the application of attacking muscle growth from all possible angles before, during and after exercise. Herculin attacks your body’s eight known angles, or pathways, to total muscle generation:
1) Nutrient Timing to maximize gains in muscle protein- Taking Herculin, Pre-Workout, significantly increases your muscle’s response to heavy training and dramatically increases your muscle’s ability to grow.
2) Stimulate Protein Synthesis – Recent research indicates that Herculin can provide an insulin spike that helps signal the onset of protein synthesis.
3) Alleviate Protein Degradation – Herculin is formulated to contain a precise ratio of key amino acids and other synergistic active ingredients that provide protection from muscle degradation and act as powerful redox agents in the body
4) Stimulate the Myogenic Regulatory Factors – Herculin MRF-4 preferentially increases MRF’s, leading to increased muscle mass. [change to the #1 point or #8 point, prefacing w/ the statement, “And, of course, #8…”]
5) Stimulate Satellite Cell Activity – Satellite cells are cellular structures that form around a muscle cell and, given the right environment and support, can develop into new muscle growth. Herculin works to stimulate satellite cell activity, leading to increased muscle fiber size and new fiber growth.
6) Enhance Myofiber Energy Restoration – Herculin provides the necessary catalyst to help enhance muscle glycogen stores, which is critical for recovery.
7) Protect Muscle Cell Membranes – Herculin provides key nutrients, in precise ratios, that protect your muscles from oxidative damage.
8) Support the Immune System – Intense training has been shown to weaken the immune system. Herculin MRF-4 contains a proprietary matrix of key ingredients shown to support healthy immune function in even the most seriously trained athletes.
By a systematic attack on these 8 known pathways to muscle growth, increased muscle is the ONLY result possible! A more in-depth description of these 8 pathways is available in Drs. Antonio and Willoughby’s new book, Herculin MRF-4™-The 1st Pre-workout Muscle GENErator. Click here to order!
A recently published study, conducted in 2001, demonstrated that a specific profile of amino acids taken before training increases amino acid uptake in skeletal muscle by 650% over a three hour period! Creating an incredibly anabolic environment for your muscles before, during and after your workouts. Herculin MRF-4 contains this exact amino acid profile. In short, Herculin MRF-4 fuels your muscles to full anabolic capacity even before your workout begins! Figure it this way: Take Herculin MRF-4, 30 minutes before workouts to begin fueling up. This fueling will last up to, and throughout a 90-minute workout Fueling continues for another hour after your workout, with additional benefits lasting up to 24 hours. There simply is no other product on the market capable of creating that kind of short- and long-term, sustained anabolic environment. Period!
If you’re working-out,
without the use of Herculin as a Pre-workout Muscle Generator, you’re
dramatically minimizing your potential to increase muscle size and strength. Any
anabolic (muscle building) response generated by your workout is minimized
significantly by how much muscle fuel was just lost during your workout, itself.
Now imagine putting 650% more fuel into your muscles to counteract your body’s
natural catabolic response to training. With Herculin MRF-4, all of your body’s
anabolic energy results in huge Net Positive Gains! Talk about a catalyst for
muscle growth!
The hidden gem to this breakthrough product lies in a patented process that takes advantage of positive and negative charges to increase bioavailability of certain ingredients up to more than 360%! Here’s how.
With proprietary and patented technology, the ingredients in Herculin are ionized when they’re mixed with water, and their molecular structure is then altered for immediate absorption by your body. The nutrients in Herculin are then more easily absorbed by your body and quickly shuttled to your muscles’ cells. Faster and more efficient than any product ever developed! In fact, a recent study at Creighton University showed that the patented delivery system used in Herculin MRF-4 was 92% available for absorption by the body, compared to just 20% availability when consumed as a standard powder mixture. This scientific study was conducted using dissolution testing, and according to the recommendation of the FDA Generic Drugs Advisory Committee, the use of dissolution testing is an in vitro surrogate marker for bioavailability.
This is the science of
Medical Delivery Technology™. And it’s no different from medical and
pharmaceutical companies struggling with ways to make drugs bioavailable to the
body…medical science is the key!
Herculin MRF-4 is for anyone who wants to gain muscle (bodybuilders, performance athletes, etc). In addition, Herculin MRF-4 can be utilized as a superior substitute for many products currently on the market:
1) Pre-Workout Energy products
2) Pro-Hormone products
3) Creatine Products
4) Isotonic drinks [list as #5]
5) Post-workout drinks [list as #4]
If you’ve searched for a boost before or after workouts, you’ve probably taken all of the products listed above at one time or another. But did you notice something? None of the aforementioned can be taken in a single dose. And none of them can provide you muscle building benefits before, during and after your training. So why take any one, or even a combination of these products when you can take just one single packet of Herculin MRF-4™, 30 minutes before training? Tripling the results, no less. The answer is you shouldn’t. And because of Herculin MRF-4, all other products are obsolete!
What other supplements will work with Herculin MRF-4™, if desired?
1) FSI Multivitamin: First thing in the morning or simultaneously with Herculin.
2) FSI HPC-3 Hybrid Protein: 30-60 minutes post-workout
3) FSI Glutamine edge: Taken either with Herculin or with your post-workout protein
4) Alpha-Ketoglutarate
(Nitic Oxide): Should be taken with Herculin MRF-4.
Dear Mr. Carnazzo
As per your request I have
reviewed the science behind Herculin MRF-4 that
Drs. Antonio and Willoughby
have formulated. When you informed me that Herculin MRF-4™ was developed by two
of the top sports scientist in the world, I knew this was going to be an
historic product that no other could compete with. Herculin MRF-4 employs all of
the latest science on muscle growth. As the former Director of Science for
NUMICO (GNC Pro Performance, MET-Rx and World Wide Sports Nutrition) I have
never seen a formula put together rooted in so much science. Drs. Antonio and
Willoughby have combed through decades of literature and discovered that
specific nutrients combined in exact ratios can enhance 8 different factors for
building new muscle. Needless to say, this is what strength and power athletes
have been looking for to naturally and safely enhance the effects of strength
training for building bigger and stronger muscles. As an avid weightlifter
myself, I am very much looking forward to using Herculin MRF-4 to enhance my
training goals.
Thank you,
Jeffrey R. Stout,
PhD
Certified Strength and Conditioning Specialist
Fellow of the American
College of Sports Medicine
Fellow of the International Society of Sports
Nutrition
Assistant
Professor
Florida Atlantic University
Exercise Science and Health
Promotion
| Supplement
Facts Serving Size 1packet (29 grams per serving)
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| * Percent Daily Values are based on a 2,000-calorie
diet Daily Value not established. |
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Ingredients: Dextrose, Tri-Creatine Citrate, Natural/Artificial Flavors, Citric Acid, Acesulfame Potassium, Sucralose, FD&C Red #40. Dissolve one packet in 16 ounces of water. |
iKevin D. Tipton, Blake B. Rasmussen, Sharon L. Miller, Steve E. Wolf, Sharla K. Owens-Stovall, Bart E. Petrini, Robert E. Wolfe. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscles to resistance exercise. Am J Physiol. Endocrinol Metab. 281: E197-E206, 2001
iiAAPS Newsletter; American Association
